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 Ranexa is a prescription medicinal drug used to deal with the signs of chest pain (Angina). Ranexa can be used on my own or with different medications.
Ranexa belongs to a category of medication known as Antianginal, Non-nitrates.
It isn't always recognised if Ranexa is secure and powerful in youngsters more youthful than 18 years of age.
What are the viable aspect outcomes of Ranexa?Ranexa might also additionally reason severe aspect outcomes including:
lightheadedness,rapid or pounding heartbeats,fluttering to your chest,very little urination,painful or tough urination,swelling to your ft or ankles,feeling tired, andshortness of breathGet clinical assist proper away, when you have any of the signs indexed above.
The maximum not unusualplace aspect outcomes of Ranexa consist of:
nausea,constipation,headache, anddizzinessTell the physician when you have any aspect impact that bothers you or that doesn't pass away.
These aren't all of the viable aspect outcomes of Ranexa. For extra information, ask your physician or pharmacist.
Call your physician for clinical recommendation approximately aspect outcomes. You might also additionally document aspect outcomes to FDA at 1-800-FDA-1088.
DESCRIPTIONRANEXA (ranolazine) Extended-launch Tablets
Ranolazine is a racemic mixture, chemically defined as 1-piperazineacetamide, N-(2,6-dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-, (±)-. It has an empirical components of C24H33N3O4, a molecular weight of 427.fifty four g/mole, and the subsequent structural components:
RANEXA® (ranolazine) Structural Formula IllustrationRanolazine is a white to off-white solid. Ranolazine is soluble in dichloromethane and methanol; sparingly soluble in tetrahydrofuran, ethanol, acetonitrile, and acetone; barely soluble in ethyl acetate, isopropanol, toluene, and ethyl ether; and really barely soluble in water.
RANEXA pills comprise 500 mg or a thousand mg of ranolazine and the subsequent inactive substances: carnauba wax, hypromellose, magnesium stearate, methacrylic acid copolymer (Type C), microcrystalline cellulose, polyethylene glycol, sodium hydroxide, and titanium dioxide. Additional inactive substances for the five hundred mg pill consist of polyvinyl alcohol, talc, Iron Oxide Yellow, and Iron Oxide Red; extra inactive substances for the a thousand mg pill consist of lactose monohydrate, triacetin, and Iron Oxide Yellow.INDICATIONSRANEXA® is indicated for the remedy of continual angina.
RANEXA can be used with beta-blockers, nitrates, calcium channel blockers, anti-platelet therapy, lipid-decreasing therapy, ACE inhibitors, and angiotensin receptor blockers.
DOSAGE AND ADMINISTRATIONDosing InformationInitiate RANEXA dosing at 500 mg two times each day and growth to a thousand mg two times each day, as wished, primarily based totally on scientific signs. Take RANEXA without or with meals. Swallow RANEXA pills whole; do now no longer crush, break, or chew.
The most endorsed each day dose of RANEXA is a thousand mg two times each day.
If a dose of RANEXA is missed, take the prescribed dose at the following scheduled time; do now no longer double the following dose.
Dose ModificationDose changes can be wished while RANEXA is taken in mixture with positive different drugs [see DRUG INTERACTIONS]. Limit the most dose of RANEXA to 500 mg two times each day in sufferers on mild CYP3A inhibitors consisting of diltiazem, verapamil, and erythromycin. Use of RANEXA with sturdy CYP3A inhibitors is contraindicated [see CONTRAINDICATIONS, DRUG INTERACTIONS]. Use of P-gp inhibitors, consisting of cyclosporine, might also additionally growth publicity to RANEXA. Titrate RANEXA primarily based totally on scientific response [see DRUG INTERACTIONS].
HOW SUPPLIEDDosage Forms And StrengthsRANEXA is furnished as film-coated, oblong-shaped, extended-launch pills withinside the following strengths:
500 mg pills are mild orange, with GSI500 on one aspecta thousand mg pills are light yellow, with GSI1000 on one aspectStorage And HandlingRANEXA is furnished as film-coated, oblong-shaped, extended-launch pills withinside the following strengths:
500 mg pills are mild orange, with GSI500 on one aspecta thousand mg pills are light yellow, with GSI1000 on one aspect RANEXA (ranolazine) extended-launch pills are to be had in: