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Tramadol dosage

This medicine is available in strengths of 50 mg, 100 mg/24 hours, 200 mg/24 hours, 300 mg/24 hours, 100 mg, 150 mg/24 hours. 

Usual adult dosage for pain (17 years or older)

  • 50 to 100 mg orally every 4-6 hours 
  • For the patients who do not require rapid onset of analgesic effect: initial dosage- 25 mg/day orally; titrate in 25 mg increments every three days to reach a dose of 25 mg four times a day; increase the quantity by 50 mg as tolerated every three days. 
  • Maximum amount- 400 mg per day

 

Usual adult dose for chronic pain

ER: 18 Years or older (tramadol-naive)- 100 mg orally once a week

  • Individually titrate in 100 mg increments every five days to an effective dose.
  • Maximum dose- 300 mg/day

 

For patients currently receiving Tramadol IR: Calculate 24-hour IR requirement and begin with a total daily ER dosage rounded down to the next lowest 100 mg/day increment orally. 

 

Conversion from other opioids: 

  • 100 mg/day ER orally
  • Individually titrate in 100 mg increments every five days to an effective dose
  • Maximum dose- 300 mg/day

 

Seek medical help if you have signs of an allergic reaction to Tramadol. Allergic reaction include hives, difficult breathing, swelling in face or throat, or a severe skin reaction involving fever, sore throat, a red or purple skin rash that spreads and cause blistering and peeling, burning in your eyes and skin pain. Tramadol can slow your breathing, just like other narcotic medicines. Too much weakness in breathing may lead to death. 

 

An attendant should give you naloxone or ask for medical help if you have slow breathing with long pauses, you are hard to wake up or have blue-colored lips. Call for medical help if you have:

 

  • Noisy breathing, shallow breathing
  • Sighing, sleep apnea
  • A slow heart rate
  • Weak pulse
  • A light-headed feeling
  • Seizures
  • Missed menstrual periods
  • Sexual problems, loss of interest in sex, impotence
  • Nausea, vomiting, loss of appetite
  • Dizziness, worsening tiredness, or weakness

 

It may cause serotonin syndrome also. Agitation, hallucinations, fever, sweating, shivering, rapid heart rate, muscle stiffness, loss of coordination, nausea, vomiting, or diarrhea are symptoms of serotonin syndrome. Serious aftereffects are more likely to occur in older adults and those who are malnourished or overweight. 

 

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