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What is hydroxychloroquine?

Hydroxychloroquineis a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

Hydroxychloroquine is not effective against all strains of malaria, or against malaria in areas where the infection has been resistant to a similar drug called chloroquine.

Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

Before taking this medicine

You should not usehydroxychloroquineif you are allergic to hydroxychloroquine or chloroquine.

High doses or long-term use of hydroxychloroquine may cause irreversible damage to your retina (the membrane layer inside your eye that helps produce vision). This could progress to permanent vision problems. The risk of retinal damage is higher in people with pre-existing eye problems, kidney disease, or people who also take tamoxifen.

To make sure hydroxychloroquine is safe for you, tell your doctor if you have ever had:

  • vision changes or damage to your retina caused by an anti-malaria medication;

  • heart disease, heart rhythm disorder (such as long QT syndrome);

  • diabetes;

  • a stomach disorder;

  • an allergy to quinine;

  • liver or kidney disease;

  • psoriasis;

  • alcoholism;

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system); or

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency.

How should I take hydroxychloroquine?

Take hydroxychloroquine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Take hydroxychloroquine with a meal or a glass of milk unless your doctor tells you otherwise.

To treat lupus or arthritis, hydroxychloroquine is usually taken daily.

To prevent malaria: Hydroxychloroquine is usually taken once per week on the same day each week. Start taking the medicine 2 weeks before entering an area where malaria is common. Keep taking the medicine during your stay and for at least 4 weeks after you leave the area.



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