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About Dilaudid Dilaudid is an opioid pain reliever that helps relieve moderate to severe pain. It acts on specific centers in the brain to give you pain relief. Do not take alcohol while taking Dilaudid. It combines alcohol with hydromorphone which could cause dangerous side effects or death. This medication is used to help relieve moderate to severe pain. Hydromorphone belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. Read the Medication ... more