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MEDICAL PHARMACY  USA Oxycodone isused to relieve moderate to severe pain. Oxycodone extended-release tablets and extended-release capsules are used to relieve severe pain in people who are expected to need pain medication around the clock for a long time and who cannot be treated with other medications.How and when to take itTake oxycodone with, or just after, a meal or snack as it's less likely to make you feel sick.It's important to swallow slow-release oxycodone tablets whole with a drink of water.Oxycodone comes as:capsule... more