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What is Hydrocodone? Hydrocodone is an antitussive (cough suppressant) and narcotic analgesic agent for the remedyof slightto fairlyintenseache. Studies suggestthat hydrocodone is as effective, or extraeffective, as codeine for cough suppression and almostequipotent to morphine for acherelief. Is hydrocodone acetaminophen over the counter? Hydrocodone is a painkiller inside the opioid family (associated with morphine). Acetaminophen is an over-the-counter remedy used to deal with aches and inflammation. They can be blended into ... more