Differences, Similarities And How to Choose Between Azithromycin 500mg and Amoxicillin from cheaponlinemedicine's blog

Almost anyone who has ever experienced bacterial sinusitis or any other type of infection can attest to taking antibiotics. Antibiotics such as azithromycin 500mg and amoxicillin are prescribed to treat bacterial infections. In contrast to viral infections, antibiotics treat bacterial infections.

Zithromax is also known as azithromycin. Macrolide antibiotics function as a group of medications. It works by binding to bacteria and preventing them from producing proteins that they need to survive. In addition to treating bacterial infections, it also helps to treat certain sexually transmitted diseases.

Amoxicillin is also known by its brand name, and it belongs to the penicillin (or beta-lactam) family of antibiotics. In order to kill bacteria, amoxicillin prevents them from forming cell walls. Bacterial infections such as ear infections, pneumonia, and throat infections respond well to amoxicillin.

Both medications are antibiotics, but they differ in many ways. Let’s take a closer look at azithromycin and amoxicillin.

Conditions treated with azithromycin and amoxicillin

Several azithromycin 500mg uses exist. It treats bacterial infections in children and adults. 

  • Those with cystic fibrosis should not use it for pneumonia, 
  • Nosocomial infections (hospital-acquired), 
  • A history of bacteremia (bacteria in the blood), 
  • Patients in hospitals, 
  • Debilitated or elderly patients, 
  • There may be deficiencies in the patient’s immune system or a lack of a spleen (asplenia).
  • Bacterial infections of chronic bronchitis
  •  sinus infection
  • Symptoms of community-acquired pneumonia
  • Patients older than 2 years who have pharyngitis/tonsillitis caused by Streptococcus pyogenes and cannot use first-line therapy.
  • infection of the skin/skin structure
  • Urinary tract infection
  • genital ulcers in men
  • Chronic ear infection

Additionally, amoxicillin helps to treat the following bacterial infections:

  • An ear, nose, or throat infection
  • affecting the genitourinary tract
  • Abrasion of the skin/skin structure
  • A disease of the lower respiratory tract
  • Male and female patients with acute uncomplicated gonorrhea due to gonorrhea
  • The eradication of pylori reduces the risk of duodenal ulcer recurrence
  • Patients with pylori infection and duodenal ulcers may benefit from amoxicillin and lansoprazole (Prevpac).

It is only appropriate to prescribe azithromycin 500mg dosage or amoxicillin if necessary. The Centers for Disease Control and Prevention (CDC) helps healthcare providers choose the right antibiotic (including the right dose and duration) and reduce unnecessary antibiotic use. Antibiotic stewardship refers to this process.

Which is more effective, azithromycin or amoxicillin?

Choosing the most effective medication requires consideration of the drug’s purpose. Take the infection’s location as an example. What type of bacteria is causing it? As you can see from the list of indications, antibiotics can treat a wide variety of infections.

One study compared a single dose of azithromycin 250mg with amoxicillin-clavulanate (Augmentin) for children with ear infections. Researchers found that both drugs were effective and well-tolerated.

As part of the second study, there were 100 patients with chronic obstructive pulmonary disease. Both drugs proved to be effective and tolerable.

You should visit your healthcare provider as soon as possible if you suspect a bacterial infection. If you have symptoms and medical history, your doctor can evaluate you and find out if any medications could interact with azithromycin or amoxicillin.

Comparing azithromycin to amoxicillin side effects

The following are the most common azithromycin 500mg side effects

Diarrhea, 

A horrid feeling, 

Abdominal discomfort

The following side effects are less frequent and occur in less than 1% of patients: 

Vomiting, 

Bloating,

Anxiety, headache 

Sleepiness, 

And rash

Penicillin sensitivity is the most common side effect of amoxicillin. It includes: 

Nausea, 

Puking,

A stomachache,

A black/hairy tongue,

Rash/hypersensitivity reactions are also possible.

Rates of occurrence are not available in percentages. With antibiotic treatment, you may be more susceptible to yeast infections. Discuss taking a probiotic with your healthcare provider. The following is not a complete list of side effects. Others may occur as well. Speak with your healthcare provider for more information.


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