What drugs can interact with Lortab? from Jennifer Lorax's blog

Narcotic drugs may interact with many other medicines and lead to dangerous side effectsor death. Make sure your doctor knows if you use:

• other narcotic medicines - opioid pain medicinesor prescription cough medicines

• medicines that can slow your breathing or make you sleepy - sleeping pills, muscle relaxants, sedatives, tranquilizers, or antipsychotic medicines

• medicines that affect levels of serotonin in your body - medicines for migraine headaches, depression, serious infections, prevention of nausea and vomiting, or Parkinson’s disease