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In the Consumer Reports survey, Purdue Pharm had the best prices for a brick-and-mortar store, while the online mail-order pharmacy Healthwarehouse.com had the lowest overall pricing. The report found the two highest-priced national retailers were CVS Health and K-Mart for the common medications they checked.

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In 1992 Synthélabo, in conjunction with the Pfizer subsidiary, Searle, was brought to the United States. Finally, it was not until 2007 that Ambien became available as a generic drug.

In 2015, the American Geriatrics Society said that Zolpidem, eszopiclone, and zaleplon met the Beers standards and should be kept away from people 65 and over.

The AGS expressed the strength of the proposal that older adults avoid Zolpidem is "strong," and the quality of evidence supporting it is "moderate."