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What is hydroxychloroquine made of?
PLAQUENIL (hydroxychloroquine sulfate) tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Inactive Ingredients: Dibasic Calcium Phosphate, Hydroxypropyl Methylcellulose, Magnesium Stearate, Polyethylene glycol 400, Polysorbate 80, Starch, Titanium Dioxide
Side Effects
Nausea, vomiting, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: slow heartbeat, symptoms of heart failure(such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), mental/mood changes (such as anxiety, depression, rare thoughts of suicide, hallucinations), hearing changes (such as ringing in the ears, hearing loss), easy bruising/bleeding, signs of infection (such as sore throat that doesn't go away, fever), signs of liver disease (such as severe stomach/abdominal pain, yellowing eyes/skin, dark urine), muscle weakness, unwanted/uncontrolled movements (including tongue/face twitching), hair loss, hair/skin color changes.
This medication may cause low blood sugar(hypoglycemia). Tell your doctor right away if you develop symptoms of low blood sugar, such as sudden sweating, shaking, hunger, blurred vision, dizziness, or tingling hands/feet. If you have diabetes, be sure to check your blood sugars regularly. Your doctor may need to adjust your diabetes medication.
Get medical help right away if you have any very serious side effects, including: severe dizziness, fainting, fast/irregular heartbeat, seizures.
This medication may cause serious eye/vision problems. The risk for these side effects is increased with long-term use of this medication and with taking this medication in high doses. Get medical help right away if you have any symptoms of serious eye problems, including: sensitivity to light, vision changes (such as light flashes/streaks, blurred vision, difficulty reading, missing areas of vision).
A very serious allergicreactionto this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Precautions
Before taking hydroxychloroquine, tell your doctor or pharmacist if you are allergic to it; or to chloroquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: a certain enzyme problem (glucose-6-phosphate dehydrogenase deficiency-G6PD), vision/eye problems, hearing problems, kidney disease, liver disease, regular alcohol use/abuse, skin problems (such as psoriasis), a certain blood disorder (porphyria), seizures.
If you have diabetes, this product may affect your blood sugar. Check your blood sugar regularly as directed and share the results with your doctor. Tell your doctor right away if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet.
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). Alcohol can also increase your risk of liver problems while you are taking this drug.
This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Hydroxychloroquine may cause a condition that affects the heart rhythm (QT prolongation). QT prolongation can rarely cause serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting) that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. Before using hydroxychloroquine, tell your doctor or pharmacist of all the drugs you take and if you have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG), family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using hydroxychloroquine safely.
Older adults may be more sensitive to the side effects of this drug, especially QT prolongation (see above).
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
This medication passes into breast milk. Consult your doctor before breast-feeding.
Interactions
See also How to Use section.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Overdose
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fast/irregular heartbeat, fainting, slow/shallow breathing, seizures.
Uses
Hydroxychloroquineis used to prevent or treat malariacaused by mosquito bites. The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Discuss the most recent information with your doctor before traveling to areas where malaria occurs.This medication is also used to treat certain auto-immune diseases (lupus, rheumatoid arthritis). It belongs to a class of medications known as How to use Hydroxychloroquine SULFATE
Take this medication by mouth, usually with food to prevent stomach upset, exactly as directed by your doctor. The dosage and length of treatment are based on your medical condition and response to treatment. In children, dosage is also based on weight.
To prevent malaria, take this medication by mouth as directed by your doctor, usually once a week on the same day each week. Mark a calendar to help you remember. This drug is usually started 1 to 2 weeks before entering the malarious area. Continue to take it weekly while in the area and for 4 to 8 weeks after leaving the area, or as directed by your doctor. To treat malaria, follow your doctor's instructions.
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See also Warning section.
Nausea, vomiting, constipation, lightheadedness, dizziness, or drowsiness may occur. Some of these side effects may decrease after you have been using this medication for a while. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To prevent constipation, eat dietary fiber, drink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you.
To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: interrupted breathing during sleep (sleep apnea), mental/mood changes (such as agitation, confusion, hallucinations), stomach/abdominal pain, difficulty urinating, signs of your adrenal glands not working well (such as loss of appetite, unusual tiredness, weight loss).
Get medical help right away if you have any very serious side effects, including: fainting, seizure, slow/shallow breathing, severe drowsiness/difficulty waking up.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Warnings & PrecautionsSee also Warning section.
Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other opioids (such as benzhydrocodone, hydromorphone, morphine, codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: brain disorders (such as head injury, tumor, seizures), breathing problems (such as asthma, sleep apnea, chronic obstructive pulmonary disease-COPD), kidney disease, liver disease, mental/mood disorders (such as confusion, depression, thoughts of suicide), personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), stomach/intestinal problems (such as blockage, constipation, diarrhea due to infection, paralytic ileus), difficulty urinating (such as due to enlarged prostate), gallbladder disease, disease of the pancreas (pancreatitis).
This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Liquid products may contain sugar and alcohol. Caution is advised if you have diabetes, alcohol dependence, liver disease, or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.
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Fioricet is a pain medication available in a combination of butalbital, acetaminophen, and caffeine. Acetaminophen (paracetamol) is a fever reducer and pain reliever. Butalbital belongs to a category of drugs called barbiturates. It relaxes muscle contractions during a tension headache.
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How to take Fioricet?
Take Fioricet precisely as per the doctor’s prescription. Read carefully and follow all the directions on the prescription label and instruction sheets or medication guides. Never use this medication for longer than prescribed. Overdose of Fioricet can cause liver damage or death.
Generic name of Fioricet: ACETAMINOPHEN 325 mg, BUTALBITAL 50 mg, CAFFEINE 40 mg
Dosage form:tablet
Dose:One or two every four hours as needed. The maximum daily dosage should not exceed six tablets.
Fioricet ER and repeated Fioricet is not prescribed because of the potential for physical dependence.
Butalbital (Fioricet) may be habit-forming. Never share Fioricet with someone else, especially someone with a past of drug abuse or addiction. It is against the lawful act to sell or give away Fioricet without a proper medical license.
Take Fioricet with milk or food if it upsets your stomach.
Store it away from heat and moisture at room temperature.
Keep track of your drug. Be aware of someone misusing it or taking it without a prescription because butalbital is a drug of abuse.
What to know before taking Fioricet?Before taking Fioricet, tell each of your medical healthcare providers if you are allergic to caffeine, acetaminophen, or butalbital; or xanthine derivatives such as theophylline or other barbiturates such as phenobarbital; or if you have other allergies.
Fioricet may have inactive ingredients, which can result in allergic reactions or other problems. Consult your pharmacist for more details.
Discuss your medical history with your doctor or pharmacist before taking this medicine, especially if you have ever had:
Porphyria (a particular enzyme disorder);
A severe breathing problem like bronchopneumonia;
Liver or kidney disease;
Mood swings or mental disorders;
An individual or family past concerning substance use disorder (such as drug abuse or addiction to alcohol or drug); or
Stomach or abdominal problems such as stomach ulcer
This medicine may cause dizziness or drowsiness. Marijuana or alcohol can make you more drowsy or dizzy. Avoid driving any vehicle or performing any activity that requires alertness.
Liquid products may have sugar, alcohol, or aspartame. You must be more careful if you have alcohol dependence, diabetes, phenylketonuria (PKU), liver disease, or another condition that requires you to avoid or limit these substances in your diet.
Before surgery or specific medical procedures such as heart stress test or restore a normal heart rhythm in a rapid unsteady heartbeat. Tell your surgeon or any other doctor treating you about all the products you use, including herbal products, prescription drugs, or nonprescription drugs.
Older adults are more likely to face this drug’s side effects, especially trouble falling asleep and drowsiness.
One should not use this medication during pregnancy. It can harm an unborn baby, or the woman can give birth to a drug-dependent baby. Babies born dependent on habit-forming drugs may have withdrawal symptoms such as vomiting, irritability, abnormal or persistent crying, diarrhea, or seizures.
This drug could cause undesirable effects on a nursing infant by passing into the breastmilk. Consult your doctor regarding breastfeeding risks.
What are the benefits of using Fioricet?This combination medicine containing Fioricet is helpful in the treatment of tension headaches.
Acetaminophen helps decrease the pain caused by a headache. Caffeine helps increase the effects of acetaminophen.
Butalbital belongs to the category of sedatives that causes sleepiness and relaxation by decreasing anxiety.
What are the side effects of Fioricet?Nausea, abdominal pain, vomiting, dry mouth, constipation, shortness of breath, tremors, lightheadedness, increased urination, drowsiness, dizziness, or trouble sleeping may occur. Take urgent medical help if any of these effects are bothersome or persist for longer than usual.
To decrease the risk of lightheadedness or dizziness, stand up slowly from a sitting or lying position.
Tell your doctor instantly if you have unlikely but severe side effects like mood swings, mental changes, seizures, fainting, fast or irregular heartbeat.
It is unlikely to have a severe allergic reaction to this drug. However, go for medical help if you notice any signs of a severe allergic reaction, including trouble breathing, rash, itching or swelling of your face, throat, or tongue, or severe dizziness.
It is not a complete list of side effects, and others may occur. Take your doctor’s medical advice regarding side effects. Report side effects to FDA at 1-800-FDA-1088.
How Fioricet works?Fioricet contains three drugs (acetaminophen, butalbital, caffeine) with different workings in pain-relieving caused by tension headaches.
Acetaminophen (paracetamol) is a fever reducer and pain reliever.
Butalbital belongs to the category of sedatives that causes sleepiness and relaxation by decreasing anxiety. It relaxes the contraction of the muscles involved in a tension headache.
Caffeine is a stimulant of the CNS (central nervous system). It improves blood flow by relaxing the muscle contractions in the blood vessel.
What to avoid while using Fioricet?Fioricet side effects can cause impairing in your thinking or reactions. Avoid performing any activity that requires alertness.
Avoid consumption of alcohol. It induces liver damage risk while taking Fioricet.
Consult your doctor before taking any pain, allergy, cold, or sleep medication. Acetaminophen (also known as APAP) contains many combination medicines. Taking specific products together can lead to a fatal overdose of acetaminophen.
While taking this medication, avoid taking caffeine pills, diet pills, or other stimulant medicines (such as ADHD drugs) without your doctor’s advice.
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