What Is The Mechanism Of Action Of Fildena 150 Mg? | Forum

Fildena 150 mg contains Sildenafil Citrate, a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED). Here’s an overview of its mechanism of action:

Primary Action: Fildena 150 mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). PDE5 is responsible for breaking down cyclic guanosine monophosphate (cGMP), a molecule that helps regulate blood flow in the penis.

Effect: By inhibiting PDE5, Fildena 150 mg increases the levels of cGMP. Elevated cGMP levels lead to prolonged relaxation of smooth muscle in the blood vessels of the penis.

Vasodilation: The increased cGMP promotes relaxation of smooth muscle and dilation of blood vessels in the penis. This allows for increased blood flow into the penile tissues during sexual arousal.

Erection: The enhanced blood flow helps achieve and maintain an erection in response to sexual stimulation.

Role of Nitric Oxide: Sexual stimulation triggers the release of nitric oxide (NO) in the penis, which initiates the production of cGMP. Sildenafil amplifies this effect by preventing the breakdown of cGMP, thereby enhancing the overall erectile response.

Onset: Fildena 150 mg typically begins to work within 30 to 60 minutes after ingestion. It should be taken about an hour before planned sexual activity for optimal results.

Duration: The effects of Fildena 150 Mg can last for up to 4 to 6 hours, providing a time window for sexual activity.

Dosage: Fildena 150 mg is usually taken as needed, not more than once per day. It should be taken with a full glass of water and can be consumed with or without food.

Interaction: For best results, avoid high-fat meals around the time of taking the medication, as this can delay its onset.

Consultation: Consult your healthcare provider before using Fildena 150 mg, especially if you have underlying health conditions or are taking other medications.

Side Effects: Potential side effects include headaches, flushing, nasal congestion, and dizziness. Serious side effects such as priapism (prolonged erection) or sudden vision changes require immediate medical attention.

Fildena 150 mg works by inhibiting PDE5, increasing the levels of cGMP, and enhancing blood flow to the penis, which helps in achieving and maintaining an erection during sexual activity. Understanding its mechanism of action can help in effectively using the medication and managing any potential side effects.